The San Francisco 49ers have some talent along their defensive line, but they could use more, and that could come early in the 2026 NFL draft.

Former 49ers defensive back Richard Sherman explained why he believes San Francisco is in a good position to win the NFC West this season.

Losing to the Green Bay Packers on Thursday Night Football lessened the San Francisco 49ers' chances of winning the NFC West. But the results of Sunday's slate of games for the rest of the teams in the division has given the 49ers a bit more leeway.

When the San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee injury, star tight end George Kittle said it was time for the offense to step up and score at least 30 points a game. The 49ers ...

Purdy was pushing the ball to all corners of the field, picking up first downs — and more — with his scrambling ability, and keeping the Niners in the right looks against a Tennessee defense that has an elite defensive tackle, a couple of other nice pieces, and little else.

Series record: 49ers lead 79-71-3. Last meeting: 49ers beat Rams 26-23, OT, in Inglewood, Calif. on Oct. 2. Last week: Rams beat Saints 34-10; 49ers beat Giants 34-24. Rams offense: overall (7), rush (18), pass (1), scoring (8). Rams defense: overall (10 ...

The San Francisco 49ers invested three picks in the 2025 NFL Draft to overhaul their defensive line, and ESPN's Field Yates projects that effort will continue next year.

Week 14 power rankings after their third straight win. See where San Francisco ranks and what it means for their NFC playoff push.

The 2025 rookies were never going to be of the “flashy” variety. It was the class that would build the foundation for the future. Add in Robert Saleh’s scheme, teaching and communication skills, and the improvements have been on full display this past month, even amid injuries.