The 49ers’ home opener has their defensive focused on Arizona’s Kyler Murray, who threw for four touchdown passes in one win last season and ran for a 50-yard touchdown in another.

When Kyler Murray is at his best, he can be a nightmare for the opposition with his ability to break off long runs, avoid sacks and extend plays doing damage to even the best NFL defenses. The San Francisco 49ers saw that first-hand last season when Murray's dual-threat ability helped the Arizona Cardinals sweep the