There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

The lab has developed ultra-small DNA nanodevices that can function inside living cells, illuminating biological processes.

Dewpoint has selected a novel small molecule to prevent the formation of abnormal TDP-43 protein clumps in ALS and other ...

Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Scientists at Stanford Medicine have discovered a treatment that can reverse cartilage loss in aging joints and even prevent arthritis after knee injuries. By blocking a protein linked to aging, the ...

Scientists have transformed enigmatic cell structures, called vaults, into storage units for messenger-RNA molecules made in ...

How much of our genome really matters? Some argue that because most of our DNA is active, it must be doing something important. Others say even random DNA would be highly active. This has now been put ...