A person is dead after a fiery crash closed both directions of an Indiana interstate. The Fisher Police Department in Indiana ...

A crash and explosion that killed one person early Wednesday morning has shut down traffic on I-69 in Hamilton County.

Did you spot a string of lights in the skies over central Indiana on Wednesday night? FOX59/CBS4 received numerous calls and ...

Chemical explosion at The Heritage Group in Indianapolis leaves one person seriously injured. Firefighters working to ventilate the facility.

Eli Lilly and Co.’s career website this month listed 254 job openings in Indianapolis and another 90 in nearby Lebanon, accounting for more than three-quarters of the 445 open positions the ...

Bryce Lindsay scored 18 points and Villanova enjoyed a second-half offensive explosion en route to an 85-67 road victory over Butler on Saturday in Indianapolis.

Supreme Court delivers major blow to Trump-era rule Medical professionals say this is the absolute worst thing you can do in ...

Far from the busy streets of Springfield and Indianapolis is a cozy destination with a charming downtown, a historic train ...

The Indianapolis-based company received U.S. regulatory approval last week for its second medicine in 18 months in what it ...

Purdy torched the Colts with a career-high five touchdowns, etching his name in 49ers history and dominating Monday Night Football.

President Donald Trump indicated the United States carried out a strike on a dock facility along Venezuela's shoreline.

Week 17 is nearly in the books, and we were treated to some excellent games. We had upsets, blowouts, divisions being ...