As President Donald Trump rolls out his “America First” policies, few countries have more to lose than Mexico.

President Trump has threatened to impose tariffs on Canada over drug trafficking, equating it with Mexico. U.S. government reports do not support the claim.

In recent remarks to the press, President Donald Trump restated his intention to impose 25% tariffs on U.S. imports from Mexico and Canada as early as Feb. 1. His reasoning: "vast" illegal immigration and "massive" amounts of fentanyl coming to the U.

Reversing the trend will require police on the reservation, which has none, and closer detox and rehabilitation centers that cater to Native Americans, tribal members and advocates say.

"If I could save at least one person out there, and I may not even know who that person is, it's a blessing in memory of my son," said Terrie Mirabal.

I think he’s going to be wise in how he does that,’ the House speaker said Monday of Trump’s warnings to America’s neighbors.

Are dropping fentanyl-related death rates concealing other issues in the fight against this brutal form of addiction?

President Claudia Sheinbaum is detaining more migrants, seizing more fentanyl and positioning her country as a key ally against China. But the U.S. stance has shifted, too.

ALAMO, N.M. (Reuters) - - Twenty-eight-year old Ambrose Begay died after a fentanyl overdose under a tree 125 yards from his home on the Alamo Navajo reservation in southern New Mexico two years ago.

The drug is increasingly manufactured in and trafficked from the U.S.’s northern neighbor, though the numbers remain small compared with Mexico.

Secretary of Commerce-designate Howard Lutnick told a Senate committee that the threat of imposing a 25% tariff was to get Canada and Mexico to “respect” the United States and stop the flow of fentanyl into the country.