A modified pig liver transplanted into a human patient appears to have functioned normally for the duration of the investigation with no signs of rejection. For 10 days, the liver performed its basic ...

Liver failure is one of the most serious and deadly medical conditions, claiming thousands of lives each year as patients in ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Doctors in China have become the first to report details about a transplant of a genetically modified pig liver into a human. The liver was transplanted last year into a person who was brain-dead, and ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

Researchers successfully implanted a genetically modified pig liver into a human, proving that such an organ can function for an extended period. The graft supported essential liver processes before ...

The transplanted portion of the genetically modified pig liver was removed after 38 days, and the patient, who had advanced liver cancer and cirrhosis, died several months later. By Roni Caryn Rabin ...

A major medical milestone has been reached with the successful transplantation of a genetically engineered pig liver into a living human. The case, reported in the Journal of Hepatology, marks the ...

A new human liver organoid microarray developed by Cincinnati Children’s and Roche recreates immune-driven liver injury in the lab. Built from patient-derived stem cells and immune cells, it ...

Of all the organs, the liver is most susceptible to drug toxicity. Drug-induced liver injury (DILI) is a leading cause of drug attrition, with over 750 FDA-approved drugs known to have a level of DILI ...