Please provide your email address to receive an email when new articles are posted on . Human GABAergic interneurons were implanted in two patients with drug-refractory focal epilepsy. Preliminary ...

The analysis of the human brain is a central goal of neuroscience. However, for methodological reasons, research has largely focused on model organisms, in particular the mouse. Now, neuroscientists ...

The hippocampus is a crucial brain region known to support the processing and storage of higher-level information, in the form of memories. In addition to allowing humans and animals to recall events ...

The signaling diversity of GABAergic interneurons to post-synaptic neurons is crucial to generate the functional heterogeneity that characterizes brain circuits. Whether this diversity applies to ...

"Our study provides a road map for understanding how and when distinct interneuron subtypes develop, giving us unprecedented insight into the biology of these cells," he said. "We can now investigate ...

Neuronal network dysfunction is increasingly recognized as an early symptom in Alzheimer’s disease (AD) and may provide new entry points for diagnosis and intervention. Here, we show that amyloid-beta ...

Dravet syndrome (DS) is a rare and severe form of epilepsy that causes intellectual disability and motor deficits and can lead to premature death. A loss-of-function mutation in one copy of SCN1A, ...