One of the major factors restricting the success of adenovirus gene therapy of cancer, particularly for intravascular delivery protocols, is the presence of neutralising anti-adenovirus antibodies.

Gene therapy for Duchenne muscular dystrophy (DMD) will require sustained expression of therapeutic dystrophins in striated muscles. Lentiviral vectors have a relatively large transgene carrying ...

The green fluorescent protein (GFP) has been established as the premier in vivo reporter for investigations of gene expression, protein localization, and cell and organism dynamics. The fungal ...

Analytical Ultracentrifugation (AUC) in the biopharmaceutical industry has traditionally been employed in the analysis of aggregation and higher order structure in protein drug products. More recently ...

The world population is suffering a lot of genetic diseases. These diseases have been very hard to tackle so far. Fortunately, since a few decades viral vectors and gene therapies became more and more ...

This is a preview. Log in through your library . Abstract The gfp (green fluorescent protein) gene has previously been used to construct a variety of reporter plasmids for Gram-positive bacteria for ...