RIKEN researchers solved a decades-old mystery of how roundworms maintain telomeres without a telomerase RNA gene. They ...
Telomeres, posted at the edges of chromosomes, protect DNA from damage. The telomerase enzyme helps maintain the length and integrity of telomeres and acts as an aging regulator. Researchers have now ...
Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres — regions of repetitive DNA sequences and a protein structure — protect the tips of chromosomes from damage. Every ...
Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...
Scientists investigate human telomere length to elucidate aging and diseases such as cancer and neurodegenerative disorders. In normal mammalian cells, a small telomeric DNA segment is lost after each ...
Patritumab deruxtecan (HER3-DXd) in active brain metastases (BM) from metastatic breast (mBC) and non–small cell lung cancers (aNSCLC), and leptomeningeal disease (LMD) from advanced solid tumors: ...
Phase III randomized trial evaluating tilsotolimod in combination with ipilimumab versus ipilimumab alone in patients with advanced refractory melanoma (ILLUMINATE 301). This is an ASCO Meeting ...
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Can we reverse aging at the cellular level?
Cellular aging, otherwise referred to as cell senescence, occurs when cells remain in a constant and terminal state of growth arrest that prevents their proliferation despite optimal growth conditions ...
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