Transforming growth factor beta 1 (TGFB1), also known as TGF-β1, CED, DPD1, and TGFB, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein ...

Transforming Growth Factor Beta (TGF‐β) signalling pathways are integral to a wide array of cellular processes, ranging from embryonic development to tissue homeostasis and immune regulation. TGF‐β ...

Ficerafusp alfa is currently being evaluated in FORTIFI-HN01, a pivotal Phase 2/3 clinical trial in patients with first line (1L) recurrent/metastatic (R/M) head and neck squamous cell carcinoma ...

When it comes to cancer metastasis, it takes two to tango. That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS ...

The US FDA has granted breakthrough therapy designation (BTD) to the bifunctional antibody ficerafusp alfa (BCA101) in ...

Role of Transforming Growth Factor Beta in Human Cancer . If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

As age increases, the pancreas changes, which increases the risk of metabolic diseases such as type 2 diabetes, digestive ...

Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full ...