Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - ...

Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing ...

Strategies to program cellular behaviors are central in synthetic biology. Scientists have developed many synthetic genetic circuits that allow engineered cells to produce therapeutic agents on demand ...

The broad-host-range pS4 plasmid harboring the inverter circuit was introduced into 6 distinct hosts from the Gammaproteobacteria class. Broad host range (BHR) synthetic biology aims to capitalize on ...

The term “integrated circuit” is no longer limited to computer chips, and the term “logic board” is no longer limited to computer chassis. These terms are being applied to biological systems by ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 11 (March 15, 2022), pp. 1-10 (10 pages) Mathematical modeling has become a major tool to guide the ...

Synthetic biology experiments suggest a “MultiFate” model for how genetically identical cells become the many different types found in complex organisms like us. The human body contains more than 200 ...

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic ...

Cells respond to intracellular and environmental cues through complex regulatory gene networks. Using synthetic biology approaches, researchers recreate these natural gene networks to discover their ...

When the physicist Richard Feynman died in 1988, he left a note on his blackboard that read, “What I cannot create, I do not understand.” Feynman may have been reflecting on the nature of scientific ...