This important study identifies PRRT2 as an auxiliary regulator of Nav channel slow inactivation, proposing that PRRT2 facilitates entry into, and delays recovery from, the slow-inactivated state. The ...
Approximately 2% of patients with irritable bowel syndrome (IBS) have a mutation of the SCN5A gene that disrupts sodium channel function, according to a genotype analysis published online March 10 in ...
Nat Clin Pract Neurol. 2008;4(3):159-169. Drug Primary clinical use Protective effect during administration in animal models? Effects of withdrawal in EAE Clinical study Phenytoin Treatment of ...