Setrusumab is a monoclonal antibody that inhibits sclerostin, a protein that negatively regulates bone development, allowing for new bone formation.

Novel Device Benefits Type 3 Osteogenesis Imperfecta In children with type 3 osteogenesis imperfecta (OI) and thoracic insufficiency syndrome (TIS), thoracic elongation surgery using a novel ...

Michaela Davert, 25, was born with osteogenesis imperfecta Type III, a condition that makes a person more likely to fracture their bones It's hard for Michaela Davert to imagine a better moment that ...

Neither study achieved its primary endpoint of reduction in annualized clinical fracture rate compared to placebo (ORBIT) or bisphosphonates ...

Clear and encouragingpercentage changes over baseline in trabecular volumetric bone mineral density measured at the radius at an early readout Expect topline 12 month data from the blinded arms of ...

RIGBY, Idaho (eastidahonews.com) — An 8-year-old girl from Rigby has already gone through more hardship than many adults have faced. During her life, Hadley Larsen has had 22 surgeries, 113 broken ...

Diff’rent Strokes actress and disability advocate Melanie Watson died at 57 on December 26, her brother Robert confirmed.

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease ...

To date, muscle function, and in particular that of the lower extremity, in OI type IV has not been investigated systematically. This study now assesses upper and lower extremity muscle function ...