Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Understanding how living cells grow, respond to stimuli, and change over time is central to modern cell biology and drug discovery. Many traditional imaging approaches rely on fluorescent labels, ...

Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods rely on adhesive or mechanical forces to hold and scan cells, which limit ...

Cell culture techniques have evolved well beyond early simplistic 2D monolayers to mimic nearly all features of a complex in vivo tissue environment. These new advanced models seek to replicate fully ...

Research on CAR-T cell states is crucial for understanding the mechanisms of immunotherapy. Previous studies in live cells have been primarily limited by phototoxicity, resolution, and throughput, ...

A research team from the School of Engineering at The Hong Kong University of Science and Technology (HKUST) has achieved a breakthrough in brain imaging by developing the world's first technology to ...

Researchers have developed a high-speed 3D imaging microscope that can capture detailed cell dynamics of an entire small whole organism at once. The ability to image 3D changes in real time over a ...

Bioengineers bridge the gap between spectroscopy developers and biologists through a systematic guide explaining modern Raman ...

Researchers at Helmholtz Munich and the Technical University of Munich have developed a new microscope that significantly improves how bioluminescent signals in living cells can be observed. The ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Figure | Working principle of Interferometric Image Scanning Microscopy (iISM). (a) Schematic of the iISM microscope and interferometric PSF detection. (b) iISM with adaptive pixel-reassignment (APR) ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...