A new statistical framework could speed up the search for rare mutations that cause common diseases, helping researchers zero ...

Uncovering how rare genetic changes disrupt brain signaling and structure, this landmark study sheds new light on the roots of schizophrenia and opens doors for future therapies. Study: Whole-exome ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ...

How fast does the human genome change? Scientists have attempted to answer this question by studying mutation rates over several generations, and they found that some parts of the human genome tend to ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...

Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different genetic paths. A new study shows that these differences can sometimes be traced ...

Biological aging undeniably affects human cognitive function. 1 However, how this happens—the underlying factors, interactions, and processes—remains unclear. He and his team want to understand how ...

Gene mutations in acute myeloid leukemia (AML) cells can guide treatment options, and machine learning can rapidly guess the existence of gene mutations based on images of leukemia cells. To solve ...

Genes are short sections of DNA that determine an animal’s traits—everything from coat color and claw strength to body shape and health. But sometimes, these genes mutate. And while the word itself ...

Prognosis and clinical management of patients with acute myeloid leukemia (AML) is determined by the genetic profile of the underlying disease. In addition to classical cytogenetic aberrations, ...