In the earliest stages of life, mammalian embryos start as a disorganized cluster of cells. As development progresses, these cells become organized into well-defined shapes and structures. This ...

Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

Doctors and scientists have long relied on microscopes to study human tissue and diagnose disease. But today's medical research produces far more information than the human eye alone can handle, ...

These images use color markers—blue for nuclei, red for cell membranes, and green for fluid—to show that spaces between cells shrink as fluid moves out during tissue compression, from left to right ...

Individually migrating cells rely on core mechanisms to turn discrete subcellular movements into coordinated action and productive translocation 1,2,3,4. For example, mesenchymal migration of a single ...