The clinical success of CRISPR-based treatments is fundamentally dependent on sophisticated gRNA targeting systems that ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR ...

The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT and ...

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in ...

Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting genetic instructions from DNA and creating proteins. With the power to execute a ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

With support from the National Institutes of Health, the COBRE Center for RNA Biology in Health and Disease will create a ...

Scientists are exploring how RNA might have jump-started life four billion years ago and how it's now advancing drug ...

National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using ...