Endocytosis is an important cellular process through which cells internalize substances such as water and nutrients. These substances are first transported as cargo to the initial sorting compartment ...
Membrane protein trafficking via endocytic pathways is essential for the regulation of receptor signalling, nutrient uptake and membrane homeostasis. Following internalisation from the plasma membrane ...
Small RNAs (sRNAs) not only play essential roles within their own cells but also act as signaling molecules, inducing trans-kingdom gene silencing between plants, fungi, and other organisms. Building ...
Endocytosis is an important cellular process through which cells internalize substances such as water and nutrients. These substances are first transported as cargo to the initial sorting compartment ...
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively ...
The Von-Hippel Lindau (VHL) gene encodes for a tumor suppressor protein, pVHL, which is responsible for the regulation of a family cancer syndrome. Mutations in pVHL render the protein non-functional ...
Brain-derived neurotrophic factor (BDNF) plays an essential role in regulating diverse neuronal functions in an activity-dependent manner. Although BDNF is synthesized primarily in neurons, astrocytes ...
Presynaptic endocytic machinery is constitutively deployed to periactive zones, indicating independent assembly pathways for the exo- and endocytic machineries of nerve terminals.