This weekend’s series, which begins Friday, marks the first meeting between the Cubs and Cardinals this season in one of baseball’s most historic rivalries. Chicago won the 2025 season series 8-5 and leads the all-time series 1,281-1,226-19.

Houston’s next game is slated for Saturday, May 23, at 2:20 p.m. ET, where they’ll once again take on the Cubs. Date Time Opponent May 23 2:20 p.m. ET Chicago Cubs May 24 2:20 p.m. ET Chicago Cubs May 25 7:05 p.

The Chicago Cubs return to Wrigley Field on Friday afternoon for the start of a weekend series against the Houston Astros. The game is scheduled to start at 2:20 p.m. ET (1:20 p.m. CT) on “Friday Night Baseball” on Apple TV+ (free trial).

You can catch the Cubs all season long with a subscription to Fubo. Regular-season games will be broadcast live locally on Marquee Sports Network and out-of-market on MLB.TV, both of which you can live stream with Fubo. The best part is that you can test ...

The first MLB game on Friday, May 22 is the first of a three-game set at Wrigley Field in Chicago where the Chicago Cubs are hosting the Houston Astros.

Houston's series opener against Alex Bregman and his new team will require a streaming subscription for fans to watch.

The latest FanDuel promo code gives new FanDuel users $150 in bonus bets if their first bet of $5 or more wins. Saturday features the best words in sports: Game 7. The San Antonio Spurs and Oklahoma City Thunder will square off in Game 7 of the NBA Western Conference Finals.