A new study, led by researchers at the University of Gothenburg, have generated the first comprehensive transcriptional atlas of neonatal mouse meningeal leukocytes, under normal conditions and after ...

Evidence that the brain harbors its own cadre of immune cells continues to grow. In the July 12 Nature Neuroscience, researchers led by Gerd Meyer zu Hörste, University Hospital Münster, Germany, ...

Delivering therapies to the brain remains a major challenge due to the limited permeability of the blood-brain barrier. In a ...

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer’s disease and ...

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection ...

Over the past decade, intensive studies have shown that the brain's meningeal lymphatic system acts as the brain's "waste disposal network," maintaining homeostasis by clearing metabolic waste and ...

Cerebrospinal fluid washes waste from the brain, eventually draining into the lymph nodes and bloodstream—but exactly how this flow bypasses the brain’s barriers to reach the periphery has remained ...

Leptomeningeal metastases (LM) occur when cancerous cells metastasize or spread to the leptomeninges, cerebral spinal fluid (CSF), or both. The meninges are thin layers of tissue surrounding and ...

Development of effective medications for central nervous system (CNS) disorders has long been plagued by a high failure rate in clinical trials. One ...

Survival in patients with brain metastasis secondary to breast cancer from Saudi Arabia. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full ...