Traumatic brain injury (TBI) is a leading cause of death and disability in children, especially those under five, with younger children more vulnerable to persistent cognitive and neuropsychological ...

Brain function requires exquisitely adapted plasticity at multiple scales, from synapses to whole-brain networks. Evidence for large-scale plasticity in functional brain networks comes from ...

A research team has established an innovative intracranial pre-olivary pretectal nucleus (OPN) optic tract injury model (pre-OPN OTI), shedding light on crucial mechanisms of functional axonal ...

Axonal regeneration: A balancing act. Following injury, neurons must navigate the trade-off between stress coping and regenerative growth. The transcription factor AhR acts as a molecular sensor, ...

Giant axonal neuropathy is a rare, autosomal recessive, pediatric, polysymptomatic, neurodegenerative disorder caused by biallelic loss-of-function variants in GAN, the gene encoding gigaxonin. We ...

A cross-sectional image of the mouse cerebral cortex in enlargement. The same method was applied as in the ferret. The cerebral cortex is shown in blue and some neurons are dyed green with GFP. In ...