The San Francisco 49ers on Sunday begin a crucial stretch of games that will ultimately decide whether they punch their ticket to the postseason again.

Dak Prescott and the Dallas Cowboys will host Jalen Hurts and the Philadelphia Eagles in Week 12 of the 2025 NFL season.

The Giants are up 27-24 in the fourth quarter following a crazy trick play touchdown reception from quarterback Jameis Winston and a 49-yard rushing touchdown from Lions running back Jahmyr Gibbs.

The San Francisco 49ers are back at Levi’s Stadium in Week 12 of the NFL season with a “Monday Night Football” matchup set against the Carolina Panthers.

The 49ers and Panthers are in the thick of the NFC playoff race. USA TODAY Sports provided updates, highlights and more from "Monday Night Football."

When the season began, the 49ers and Panthers showdown on Monday Night Football looked like a throwaway matchup between an aimless Carolina club and a potential Super Bowl contending San Francisco clu...

Purdy led an efficient offense, throwing for 200 yards and three touchdowns, while Christian McCaffrey had 81 yards and two touchdowns on 13 carries and caught five passes for 40 yards and another sco...